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Professor Xue-Feng YUAN

Data:[2017-11-03]  Source:

XUE-FENG YUAN PhD CPhys FInstP FRSC Dean Advanced Institute of Engineering Science for Intelligent Manufacturing Guangzhou University Guangzhou, P. R. China.

Professor Xue-Feng Yuan is a Chartered Physicist, a Fellow of the Institute of Physics and a Fellow of Royal Society Chemistry. He has joined Guangzhou University as Professor in Systems Rheology to establish Advanced Institute of Engineering Science for Intelligent Manufacturing since November 2016 after nearly three years service as the Founding Director of National Supercomputer Centre in Guangzhou for running “Tianhe-2” supercomputer, which was ranked the world fastest supercomputer six times successively from June 2013 to June 2016.  He is a chief co-ordinator of ICT&HPC thematic area for the BRICS STI Framework Programme and a member of the Global Initiative Working Group of the European Commission eInfraCentral Coordination Action. Also he serves as a Council Member of Chinese Society of Rheology and Chairman of the HPC committee of the Guangdong Society of Computer.

Professor Yuan has over 30 years research experience in experimental, theoretical and computational rheology of soft condensed matter, recently its applications in biology and medicine. He obtained PhD from the Victoria University of Manchester, UK in 1989. He then worked as a postdoctoral research associate at Theory of Condensed Matter Centre, Cavendish Laboratory, the University of Cambridge, UK for five years, and also worked as a Kao Corporation visiting scientist and as a part-time lecturer in Department of Applied Physics, Nagoya University, Japan. He won a prestigious 5-year EPSRC Advanced Research Fellowship in 1996 and worked in Centre of Theoretical Physics, Department of Physics, the University of Bristol, UK till Sept. 1999, then joined Department of Mechanical Engineering, King’s College London, UK. He took a Readership in Biochemical Physics at Manchester Interdisciplinary Biocentre, School of Chemical Engineering and Analytical Science, the University of Manchester, UK, in 2004. He served various EPSRC Prioritisation Panels for Processing Engineering, Structural Materials, Physics, Fighting against Crime Programme, and MRC Prioritisation Panel for Discipline Hopping Grants. He acts as an external PhD thesis examiner for the University of Cambridge, Warwick University, University of Sheffield and Swansea University.


By taking systems rheology approach we are able to understand and to predict the equilibrium and non-equilibrium properties of soft matter and complex fluids from the microscopic level, and to develop novel applications in biomedical and bioprocessing. Miniaturization of desktop rheometer into Rheo-chip platform is of significance to high throughput analysis of formulation design and processing control of materials using very small amount of samples. Parallel computing codes for large scale simulations of complex fluids will facilitate digital design of fluid formulations and manufacturing processes for a wide range of industrial applications such as additive manufacturing (3D printing), high-speed fiber spinning and coating, drug delivery, lubrication, adhesion, spraying, painting, microchip production, manufacture of high-energy lithium batteries and photovoltaic cells, photographic products and biocompatible products, extraction of oil from porous rock and others, production of biomass and geothermal energy, hence they play a key role in the third industrial revolution.

On experimental rheology, designed, and successfully led a research team that constructed and validated a unique Rheo-chip rheometer (prototype) which can access deformation rate up to 106 s-1 and frequency up to 100 Hz (PCT/GB2011/051476). The already achieved technical specifications are at least one or two orders of magnitude higher than those of commercial rheometers, and with further benefit of minimum inertial effect. Such a miniaturised rheometer uses tiny amount (less than 500 microliter) of sample, has higher sensitivity and better performance, and is suitable for high throughput rheological characterisation under shear flow, extensional flow and industrial benchmark flow problems. It also has an optical window for in-situ probing structure evolution of complex fluids under various flow conditions.

In computational and theoretical rheology,  1) developed a framework to fully integrate our novel Lagrangian-Eulerian strategy for modelling complex fluid flows, finite volume methods (with high order discrete schemes), discrete Boltzmann method, smooth particle hydrodynamics method, immersed boundary method, coarse-grained meso-dynamic method with a unified molecular theory, non-equilibrium molecular dynamics into a multiple scale (open sourced C++) simulation platform for extra-large scale parallel modelling of strongly correlated dynamics of soft matter and complex fluids in multi-core parallel computing environment. It will be fully integrated with the Rheo-chip platform for digital manufacturing from molecular and formulation design to processing optimisation; 2) proposed a novel method to solve viscoelastic fluid flow using the lattice Boltzmann method. It opens a new door for multiple scale parallel computing of nonlinear dynamics of complex fluids and beyond; 3) proposed a comprehensive two-fluid model to study strong coupling between dynamics of phase transitions and viscoelastic fluid flow and developed efficient flow solver for carrying out predictive modelling of binary polymer blends under strong flow conditions, hence successfully reproduced the generic feature of the shear-induced phase transitions observed in complex fluids, and for the first time, revealed a direct correlation between microstructural evolution in complex fluids and the rheological response, and thus reveal the dynamic pathway of phase transition under flow and allow prediction of the morphology of solidified materials.


1.W. Yi, D. Corbett, X-F. Yuan, “Lateral migration of neutrally-buoyant particles in direct channel flows”, submitted to Physical Review E.

2.A. Lanzaro, D. Corbett and X-F. Yuan, “Non-linear Dynamics of semi-dilute PAAm Solutions in a Microfluidic 3D Cross-slot Flow Geometry”, J. Non-Newtonian Fluid Mechanics, 242, 57-65 (2017).

3.Y. Wang, F. Serracino-Inglott, X. Yi, X. Yang and X-F. Yuan, "An Interactive Computer-based Simulation System for Endovascular Aneurysm Repair Surgeries", Computer Animation and Virtual Worlds, 27, 290-300(2016).

4.Y. Wang, F. Serracino-Inglott, X. Yi, X-F. Yuan and X. Yang, "Real-time Simulation of Catheterization in Endovascular Surgeries", Computer Animation and Virtual Worlds, 27, 185-194(2016).

5.W. Yi, D. Corbett and X-F. Yuan, "An improved-Rhie-Chow interpolation scheme for the smoothed-interface immersed boundary method", International Journal for Numerical Methods in Fluids, 82(11), 770-795(2016).

6.W. Yi, D. Corbett and X-F. Yuan, "A sharp-interface Cartesian grid method for viscoelastic fluid flow in complex geometry”, J. Non-Newtonian Fluid Mechanics, 234, 82-104 (2016).

7.Y. Cao, W. Yang, X-W. Guo, X. Xu, J. Chen, X. Yang and X-F. Yuan, "Role of Non-monotonic Constitutive Curves in Extrusion Instabilities", International Journal of Polymer Science, Vol.2015, DOI:10.1155/2015/312839, 8 pages (2015).

8.W Yang, W. Yi, X Ren, L. Xu, X. Xu and X-F. Yuan, “Toward large scale parallel computer simulation of viscoelastic fluid flow: a study of benchmark flow problems”, J. Non-Newtonian Fluid Mechanics, 222, 82-95 (2015), DOI: 10.1016/j.jnnfm.2014.09.004.

9.T. Hodgkinson, X-F. Yuan and A. Bayat, “Electrospinning silk fibroin fiber diameter influences in vitro dermal fibroblast behaviour and promotes healing of ex vivo wound models”, Journal of Tissue Engineering, 5, 1-13(2014), DOI: 10.1177/2041731414551661.

10.X-W. Guo, S. Zou, X. Yang, X-F. Yuan, M. Wang, “Interface instability and chaotic rheological responses in binary polymer mixtures under shear flow”, RSC Advances, 4, 61167-61177 (2014).

11.A. Lanzaro, Z. Li, X-F. Yuan, “Quantitative characterisation of high molecular weight polymer solutions in microfluidic hyperbolic contraction flow”, Microfluidics and Nanofluidics, 1-10(2014), DOI: 10.1007/s10404-014-1474-z.

12.S. Zou, X-F. Yuan, X. Yang, W. Yi and X. Xu, “An integrated lattice Boltzmann and finite volume method for the simulation of nonlinear viscoelastic fluid flows”, J. Non-Newtonian Fluid Mechanics, 211, 99-113 (2014).

13.T. Hodgkinson, Y. Chen, A. Bayat and X-F. Yuan, “Rheology and electrospinning of regenerated Bombyx mori silk fibroin aqueous solutions”, Biomacromolecules, 15(4), 1288-1298 (2014).

14. A. Lanzaro, X-F. Yuan, “A quantitative analysis of spatial extensional rate distribution in nonlinear viscoelastic flows”, J. Non-Newtonian Fluid Mechanics, 207, 32-41 (2014).

15.S.C. Omowunmi and X-F. Yuan, “Time-dependent nonlinear dynamics of polymer solutions in microfluidic contraction flow – A numerical study on the role of elongational viscosity”, Rheologica Acta, 52, 337-354 (2013).

16.X-F. Yuan, “Rheometry Apparatus”, Patent Application No. 1013044.1 (2010), PCT/GB2011/051476 (2011) and WO2012/017246 A2 (2012).

17.L. Wang, H. Xie, X. Qiao, A. Goffin, T. Hodgkinson, X-F. Yuan, K. Sun and G. G. Fuller; “Interfacial rheology of natural silk fibroin at air/water and oil/water interfaces”, Langmuir, 22, 459-467 (2011).

18.A. Lanzaro, X-F. Yuan, “Effects of the contraction ratio on non-linear dynamics of semi-dilute highly polydisperse PAAm solutions in microfluidics”, J. Non-Newtonian Fluid Mechanics, 166, 1064-1075 (2011).

19.Z. Li, X-F. Yuan, S. Haward, J. Odell and S. Yeates, “Non-linear dynamics of semi-dilute polydisperse polymer solutions in microfluidics: effects of flow geometry”, Rheologica Acta, 50, 277-290 (2011).

20.Z. Li, X-F. Yuan, S. Haward, J. Odell and S. Yeates, “Non-linear dynamics of semi-dilute polydisperse polymer solutions in microfluidics: a study of benchmark flow problem”, J. Non-Newtonian Fluid Mechanics, 166, 951-963 (2011).

21.S. Haward, Z. Li, D Lighter, B. Thomas, J. Odell, X-F. Yuan, “Flow of dilute to semi-dilute polystyrene solutions through a benchmark 8:1 planar abrupt micro-contraction”, J. Non-Newtonian Fluid Mechanics, 165, 1654-1669 (2010).

22.S. Haward, J. Odell, Z. Li, X-F. Yuan, “The rheology of polymer solution elastic strand in extensional flow”, Rheologica Acta, 49, 781-788 (2010).

23.S. Haward, J. Odell, Z. Li, X-F. Yuan, “Extensional rheology of dilute polymer solutions in oscillatory cross-slot flow: the transient behaviour of birefringent strands”, Rheologica Acta, 49, 633-645 (2010).

24.S.C. Omowunmi and X-F. Yuan, “Modelling the three-dimensional flow of a semi-dilute polymer solution in microfluidics – on the effect of aspect ratio”, Rheologica Acta, 49, 585-595 (2010).

25.G. O. Aloku and X-F. Yuan, “Numerical simulation of polymer foaming process in extrusion flow”, Chemical Engineering Science, 65, 3749-3761 (2010).

26.K. Sato, X-F. Yuan and T. Kawakatsu, “Why does shear banding behave like first-order phase transitions? Derivation of a potential from a mechanical constitutive model”, European Physical Journal E, 31, 135-144 (2010).

27.T. Hodgkinson, X-F. Yuan and A. Bayat, “Adult stem cells in tissue engineering”, Expert Review of Medical Devices, 6, 621-640 (2009).

28.C. Sobajo, F. Behzad, X-F. Yuan, A. Bayat, “Silk: a potential medium for tissue engineering”, ePlasty: Open Access Journal of Plastic and Reconstructive Surgery”, 8, 438-446 (2008).

29.A. Kelarakis, V. Havredaki, X-F. Yuan, C. Chaibundit and C. Booth, “Aqueous gels of triblock copolymers of ethylene oxide and 1,2-butylene oxide (type BEB) studied by rheometry”, Macromolecular Chemistry and Physics, 207, 903-909 (2006).

30.D. Mistry, T. Annable, X-F. Yuan, C. Booth, “Rheological behaviour of aqueous micellar solutions of a triblock copolymers of ethylene oxide and 1,2-butylene oxide: B10E410B10, Langmuir, 22, 2986-2992 (2006).

31.R Pathansali, A A Mangoni, B. Creagh-Brown, Z.C. Lan, G.L. Ngow, X-F. Yuan, E L Ouldred, R Sherwood, C.G. Swift, S H D Jackson, "Effects of folic acid supplementation on psychomotor performance and blood rheology in healthy elderly subjects", Archives of Gerontology and Geriatrics, 43, 127-137 (2006).

32.X. Shan, X-F. Yuan, H. Chen, "Kinetic representation of hydrodynamics: A way beyond the Navier-Stokes equation", J. Fluid Mech., 550, 413-441 (2006).

33.S. Lacey, T. P. Ford, X-F. Yuan, M. Sherriff and T. Watson, “The effect of temperature on viscosity of root canal sealers”, International Endodontic Journal, 39, 860-866 (2006).

34.J.Y. Lee, G.G. Fuller, N. Hudson and X-F. Yuan, "Investigation of shear bands in worm-like micellar solution by point-wise flow-induced birefringence measurement", J. of Rheology, 49, 537-550 (2005).

35.V. Castelletto, I. W. Hamley, X-F. Yuan, A. Kelarakis and C. Booth, "Structure and rheology of aqueous micellar gels formed from an associative triblock poly(oxybutylene)-poly(oxyethylene)-poly(oxybutylene) copolymer", Soft Matter, 1, 138-145 (2005).

36.C. Chaibundit, P. Sumanatrakool, S Chinchew, P. Kanatharana, C. Booth and X-F. Yuan, "Association properties of diblock copolymer of ethylene oxide and 1,2-butylene oxide: E17B12 in aqueous solution", Journal of Colloid and Interface Science, 283, 544-554 (2005).


Names of Investigators

Project Titles

Funding Sources and Duration


X-F Yuan (PI),

A. Golovanov, A. Revell and R. Curtis

Bioprocessing of High Concentration Protein Solutions: Quality by Digital Design Approach

BBSRC/BRIC2/2 (BB/K011146/1), April 2013 – March 2016


X-F Yuan (PI)

Validation of Rheo-chip Technology through Rheometric Characterisation of Structured Fluids with Yield Stress

EPSRC KTA Concept and Feasibility Study Grant

July – Dec 2012


X-F Yuan (PI)


F Serracino-Inglott (surgeon)

Interactive in-silico Platform for Optimising Surgical Procedure of Abdominal Aortic Aneurysm Repair and Evaluation of Stent Performance


April 2012 – July 2012


X-F Yuan (PI)

Rheo-chip Technology

UMIP PoP fund, March 2012-Feb. 2013


X-F Yuan (PI)

Rheo-chip Based Microrheometer

EPSRC KTA Concept and Feasibility Study Grant

July – Dec 2011


X-F Yuan (PI) 


C. Ward

Microfluidic Modulation of Embryonic Stem Cell Differentiation in Well-Defined Microscopic Flow

EPSRC KTA Concept and Feasibility Study Grant

February – July 2011


X-F Yuan (PI) 

and A.M. Heagerty (surgeon)

Development of an Integrated Platform for Quantitative Analysis of Haemodynamics in Small Blood Vessels

Joint MRC, EPSRC & BBSRC grant (G0902318)

October 2010 – September 2011


X-F Yuan (Academic Leader) and Gordon Carlson (surgeon)

Better Design of Colostomy Bag

MIMIT Grant, Sept 2010 – April 2011


X-F Yuan (Academic Leader) and 

F Serracino-Inglott (surgeon)

An in-Vitro Quantitative Characterisation Platform for Optimisation of Abdominal Aortic Aneurysm Repair and Novel Design of Stent-grafts

MIMIT Grant, April 2009 – October 2010


X-F Yuan (PI)

SG Yeates (Chemistry) and Linkam Scientific Ltd

Rheology of Complex Fluids in Microscopic Flows: Quantitative Characterisation from Molecular Dynamics to Fluid Flows

EPSRC Grant (EP/E032699), May 2007 – November 2010


X-F Yuan (PI)

Dynamics of Foam Growth in Polymeric Fluid Flows

Industrial Grant: Armacell International GMBH, Oct. 2005 – Sept. 2009


X-F Yuan (PI),

M Yianneskis, and ICI Technology, Kodak Ltd., ZENECA Agrochemicals

Quantitative Characterisation of Complex Fluids in Strong Flow Fields


(GR/ N39036/01)

Nov 2000 – April 2004


X-F Yuan (PI),

M Yianneskis, and ICI Technology, Kodak Ltd., ZENECA Agrochemicals

Development of Optical Techniques for characterisation of Complex Fluids


(GR/ N35373/01)

Nov 2000 – April 2004


X-F Yuan (PI)

Development of a Unified Lattice Boltzmann Model for Modelling Industrial Flow

EPSRC Grant (GR/M94755/01)

May 2000 – Oct 2002


X-F Yuan (PI)

Dynamic Modelling Microstructure Formation of Soft Solid Materials and the Effect Flow on the Structure Evolution

EPSRC Grant (GR/L51010)

Oct 1997 – Feb 2001


X-F Yuan (PI)

Computer Simulations and Statistical Mechanics of Complex Fluids

EPSRC Grant (B/96/AF/2152)

March 1997 – March 2002


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